Applying CBD topically vs ingesting


The increased availability of CBD products has prompted different consuming techniques, including topical application, swallowing, vaping, and sublingual administration.

Topical application and oral intake are the prevalent methods of delivery depending on the intended use or dosage. However, both attempts to achieve homeostasis based on your expectations and usage, whether separately or cooperatively.

What Is Topical CBD

Refers to CBD-infused lotions, salves, creams, or oils designed to be administered directly to tight muscles, aching or stiff joints, or inflammatory sites. The bioavailability of topical and transdermal products is approximately 45 percent. Topical CBD can take anything between 15 mins - 1 hour to penetrate and feel in the afflicted area. CBD is absorbed when applied to the skin but does not enter the bloodstream like it does when taken orally or through other means. It is frequently used for localized muscle tension, stiff joints, or inflammation since it is absorbed into the tissue where it is administered.

Ingestible CBD

Those who wish to use CBD orally should seek the ingestible one. The mouth commonly consumes CBD in two ways: underneath the tongue and ingestion. The quick absorption rate and ease of usage sublingually approach are also lauded. Insert the CBD product beneath the tongue for 30-60 seconds and hold it there. While CBD is held beneath the tongue, it absorbs through the mouth's mucous membranes and enters the circulation, where it binds to cannabinoid receptors and begins to work. Within 30 minutes of using oil-based CBD tinctures, you will notice the results.

Try a water-based CBD tincture like A88CBDTM if you want to feel the effects faster. It has a unique water-soluble composition called C10TM that enables a quick onset and results in just 10 minutes. Ingestion is another popular way to consume CBD products. The CBD product is swallowed in this technique. The active substances move through your digestive system and finally metabolize your liver. CBD molecules are transported to the circulation from the liver. CBD capsules are an excellent choice if you want to ingest CBD discreetly. This very water-soluble composition, C10TM, is used in A88CBDTM capsules, allowing you to start reaping the benefits in as little as 10 minutes!

Bioavailability Topically Vs. Ingested

Bioavailability refers to your body's capacity to absorb CBD from the application area into the bloodstream. Certain hemp CBD products have a higher bioavailability than others because they allow more CBD to enter the bloodstream without being metabolized or broken down. The other benefits from CB are dependent on why you use it. CBD topicals have low bioavailability; however, they directly absorb the afflicted area. The skin acts as a barrier, preventing substances and components from entering the body. In contrast, CBD topical molecules do not need to enter the blood since they bind and excite the CB2 receptors in the skin, which are parts of the endocannabinoid system (ECS).


More of the actual CBD molecule (often up to 80 percent or more) may be absorbed and utilized by the body depending on production, such as a water-based nano CBD particle vs. an oil-based CBD. Compared to oil-based CBD choices, nanoparticle water-based CBD has better bioavailability, absorption, and onset times.

  • Many other factors also influence absorption.
  • CBD has high lipophilicity (a fat-soluble nature).
  • The CBD extraction procedure was utilized to isolate it.
  • CBD consumption method (sublingual tinctures, edibles, combustion, etc.)
  • Natural biological distinctions exist in each individual.
  • Natural variances in organ tissue (for example, alveolar/lungs, dermal/skin, or gastric/the stomach and liver).
  • Consumption time

Which One Is the Best

CBD applied topically binds with the cannabinoid receptors in the administered area. It does not absorb into the bloodstream, making this type of medicine excellent for certain treatments and regions. This product is typically used to relieve tired muscles and skin problems. On the other hand, Ingesting CBD allows the product to be eaten and absorbed into the blood circulation. This allows CBD to interact with the cannabinoid receptors all over the body.

Possible Side Effects

CBD is possibly safe to use inadequate doses when taken orally. Doses of 200 mg per day have been successfully administered for 13 weeks. Dry mouth, low blood pressure, lightheadedness, sleepiness, and fatigue are all possible adverse effects of CBD. Epidiolex, a prescription version, has been linked to liver harm. There isn't enough solid data to say CBD is safe or has potential adverse effects when applied topically.


CBD can be administered in various methods, the most common of which are topical and oral. Both of these strategies have advantages and downsides that one must consider. There are a variety of CBD topicals and CBD ingestible on the market that one can experiment with. This will assist users with these items and let them select what works best for them. Seek professional assistance if you are new to CBD or unsure how to choose the best product for your needs.


Herkenne, C., Alberti, I., Naik, A., Kalia, Y. N., Mathy, F. X., Préat, V., & Guy, R. H. (2008). In vivo methods for the assessment of topical drug bioavailability. Pharmaceutical Research, 25(1), 87-103.

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